human TNFRSF6B shRNA silencing AAV

Name 
AAV-h-TNFRSF6B-shRNA
Cat No 
shAAV-222079
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TNFRSF6B.

shAAV-222079
AAV-h-TNFRSF6B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TNFRSF6B (TNF receptor superfamily member 6b). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DCR3; DJ583P15.1.1; M68; M68E; TR6
Description (Vector)
TNFRSF6B belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript.
Gene ID
8771
Gene Name (Vector)
TNF receptor superfamily member 6b
Gene Symbol
TNFRSF6B
HGNC ID
HGNC:11921
ORF Size (aa)
903
RefSeq ID
NM_003823
RefSeq Synonyms
NM_003823, BC034349, BC017065,
Species
human
UniGene ID
Hs.434878

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.