human RRAGB Over-expression AAV

Name 
AAV-h-RRAGB
Cat No 
AAV-221990
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RRAGB.

AAV-221990
AAV-h-RRAGB

Ready-to-use AAV expressing Human RRAGB (Ras related GTP binding B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA465E19.1; RAGB
Description (Vector)
Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified.
Gene ID
10325
Gene Name (Vector)
Ras related GTP binding B
Gene Symbol
RRAGB
HGNC ID
HGNC:19901
ORF Size (aa)
1041
ORF Size (bp)
1041 bp
RefSeq ID
NM_006064
RefSeq Synonyms
NM_016656, NM_006064, BC034726,
Species
human
UniGene ID
Hs.50282

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.