human RP2 Over-expression AAV

Name 
AAV-h-RP2
Cat No 
AAV-221521
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RP2.

AAV-221521
AAV-h-RP2

Ready-to-use AAV expressing Human RP2 (retinitis pigmentosa 2 (X-linked recessive)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DELXp11.3; NM23-H10; NME10; TBCCD2; XRP2
Description (Vector)
The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death
Gene ID
6102
Gene Name (Vector)
retinitis pigmentosa 2 (X-linked recessive)
Gene Symbol
RP2
HGNC ID
HGNC:10274
ORF Size (aa)
1053
RefSeq ID
NM_006915
RefSeq Synonyms
NM_006915, BC053530, BC043348,
Species
human
UniGene ID
Hs.44766

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.