human RP2 shRNA silencing Adenovirus

Name 
Ad-h-RP2-shRNA
Cat No 
shADV-221521
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RP2.

shADV-221521
Ad-h-RP2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RP2 (retinitis pigmentosa 2 (X-linked recessive)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DELXp11.3; NM23-H10; NME10; TBCCD2; XRP2
Description (Vector)
The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death
Gene ID
6102
Gene Name (Vector)
retinitis pigmentosa 2 (X-linked recessive)
Gene Symbol
RP2
HGNC ID
HGNC:10274
ORF Size (aa)
1053
RefSeq ID
NM_006915
RefSeq Synonyms
NM_006915, BC053530, BC043348,
Species
human
UniGene ID
Hs.44766

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.