human PVRL4 Over-expression AAV

Name 
AAV-h-PVRL4
Cat No 
AAV-220421
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NECTIN4.

AAV-220421
AAV-h-PVRL4

Ready-to-use AAV expressing Human NECTIN4 (nectin cell adhesion molecule 4). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EDSS1; LNIR; nectin-4; PRR4; PVRL4
Description (Vector)
PVRL4 encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
Gene ID
81607
Gene Name (Vector)
nectin cell adhesion molecule 4
Gene Symbol
NECTIN4
HGNC ID
HGNC:19688
ORF Size (aa)
1533
ORF Size (bp)
1533 bp
RefSeq ID
NM_030916
RefSeq Synonyms
NM_030916, BC010423,
Species
human
UniGene ID
Hs.492490

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.