human PLUNC Over-expression AAV

Name
AAV-h-PLUNC

Cat No
AAV-219242

Availability
4-5 weeks

This is an AAV expressing Human BPIFA1.

AAV-219242

AAV-h-PLUNC

Ready-to-use AAV expressing Human BPIFA1 (BPI fold containing family A member 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

bA49G10.5; LUNX; NASG; PLUNC; SPLUNC1; SPURT

Description (Vector)

BPIFA1 is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this gene is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known.

Gene ID

51297

Gene Name (Vector)

BPI fold containing family A member 1

Gene Symbol

BPIFA1

HGNC ID

HGNC:15749

ORF Size (aa)

771

ORF Size (bp)

771 bp

RefSeq ID

NM_016583

RefSeq Synonyms

NM_130852, NM_016583, NM_001243193, BC012549,

Species

human

UniGene ID

Hs.211092

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.