human PLRG1 Over-expression AAV

Name 
AAV-h-PLRG1
Cat No 
AAV-219224
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PLRG1.

AAV-219224
AAV-h-PLRG1

Ready-to-use AAV expressing Human PLRG1 (pleiotropic regulator 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Cwc1; pleiotropic regulator 1; pleiotropic regulator 1 (PRL1 homolog, Arabidopsis); PRL1; PRP46; PRPF46; TANGO4; transport and golgi organization 4 homolog
Description (eCommerce)
Pleiotropic regulator 1 (PLRG1) has been shown to be a part of sub-spliceosomal protein complexes. It is highly conserved across species and is essential for pre-mRNA splicing. PLRG1 interacts with human CDC5. This interaction has also been shown to be essential to pre-mRNA splicing.
Description (Vector)
PLRG1 encodes a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
5356
Gene Name (eCommerce)
pleiotropic regulator 1
Gene Name (Vector)
pleiotropic regulator 1
Gene Symbol
PLRG1
HGNC ID
HGNC:9089
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1518
ORF Size (bp)
1518 bp
Protein Name (eCommerce)
Pleiotropic regulator 1
RefSeq ID
NM_002669
RefSeq Synonyms
NM_002669, NM_001201564, BC106004, BC020786,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Processing,Signal Transduction,Spliceosome
Research Areas (Faceted)
signal_transduction,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
Pleiotropic regulator 1 (PLRG1) has been shown to be a part of sub-spliceosomal protein complexes. It is highly conserved across species and is essential for pre-mRNA splicing. PLRG1 interacts with human CDC5. This interaction has also been shown to be essential to pre-mRNA splicing.
UniGene ID
Hs.249996
UniProt ID (eCommerce)
O43660

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.