human PIGR Over-expression AAV

Name 
AAV-h-PIGR
Cat No 
AAV-218920
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PIGR.

AAV-218920
AAV-h-PIGR

Ready-to-use AAV expressing Human PIGR (polymeric immunoglobulin receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
PIGR is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.
Gene ID
5284
Gene Name (Vector)
polymeric immunoglobulin receptor
Gene Symbol
PIGR
HGNC ID
HGNC:8968
ORF Size (aa)
2295
ORF Size (bp)
2295 bp
RefSeq ID
NM_002644
RefSeq Synonyms
NM_002644, BC110495, BC110494,
Species
human
UniGene ID
Hs.497589

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.