human PIAS1 Over-expression AAV

Name 
AAV-h-PIAS1
Cat No 
AAV-218884
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PIAS1.

AAV-218884
AAV-h-PIAS1

Ready-to-use AAV expressing Human PIAS1 (protein inhibitor of activated STAT 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DDXBP1; GBP; GU/RH-II; ZMIZ3
Description (Vector)
PIAS1 encodes a member of the mammalian PIAS (protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)) family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.
Gene ID
8554
Gene Name (Vector)
protein inhibitor of activated STAT 1
Gene Symbol
PIAS1
HGNC ID
HGNC:2752
ORF Size (aa)
1956
ORF Size (bp)
1956 bp
RefSeq ID
NM_016166
RefSeq Synonyms
NM_016166, NM_001320687, BC121797, BC118587,
Species
human
UniGene ID
Hs.162458

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.