human PHOX2B Over-expression AAV

Name 
AAV-h-PHOX2B
Cat No 
AAV-218856
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human PHOX2B.

AAV-218856
AAV-h-PHOX2B

Ready-to-use AAV expressing Human PHOX2B (paired like homeobox 2b). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NBLST2; NBPhox; PMX2B
Description (Vector)
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element.
Gene ID
8929
Gene Name (Vector)
paired like homeobox 2b
Gene Symbol
PHOX2B
HGNC ID
HGNC:9143
ORF Size (aa)
945
RefSeq ID
NM_003924
RefSeq Synonyms
NM_003924, BC017199,
Species
human
UniGene ID
Hs.87202

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.