AAV with mIP2 promoter driven EYFP
This AAV expresses EYFP driven by an islet mIP2 promoter.
This promoter is based on the 1.1 Kb regulatory region of mouse pre-proinsulin II gene, also known as ins2, ins-2, ins-II, insulin-II, or Mody4. It is commonly used for beta cell-specific gene expression in the pancreatic islet. (m)INS2 promoter is also referred as the mIP2 or mIP2 promoter.
YFP is the longest wavelength-emitting variants of Aequorea GFP. The enhanced version, EYFP, has become one of the brightest and most widely utilized of the fluorescent proteins with an Excitation/Emission spectrum centered around 514nm/527nm. Other fluorescent proteins with similar emission spectrums include Topaz, Venus, Citrine and mCitrine.
Ready-to-use AAV expressing EYFP driven by an islet mIP2 promoter. Available in AAV1, AAV2, AAV5, AAV6, AAV8, AAV9, AAV-DJ and other serotypes.