AAV with aMHC promoter driven EYFP
This AAV expresses EYFP driven by a cardiac aMHC promoter.
αMHC(0.4) promoter is derived from the murine α-MHC gene (alpha-myosin heavy chain) and drives cardiac-specific expression. The length of this promoter is 0.4 Kb. Based on studies in primary cardiomyocytes, this aMHC(0.4) promoter gives an expression level that is comparable to that of a CMV promoter.
YFP is the longest wavelength-emitting variants of Aequorea GFP. The enhanced version, EYFP, has become one of the brightest and most widely utilized of the fluorescent proteins with an Excitation/Emission spectrum centered around 514nm/527nm. Other fluorescent proteins with similar emission spectrums include Topaz, Venus, Citrine and mCitrine.
Ready-to-use AAV expressing EYFP driven by a cardiac aMHC promoter. Available in AAV1, AAV2, AAV5, AAV6, AAV8, AAV9, AAV-DJ and other serotypes.