rat CYP24A1 shRNA silencing Adenovirus

Name 
Ad-r-CYP24A1-shRNA
Cat No 
shADV-294490
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Rat Cyp24a1.

shADV-294490
Ad-r-CYP24A1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Cyp24a1 (cytochrome P450, family 24, subfamily a, polypeptide 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
24-OHase; 24R-Ohase; Cyp24; P450-CC24; VITD12
Description (Vector)
Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
Gene ID
25279
Gene Name (Vector)
cytochrome P450, family 24, subfamily a, polypeptide 1
Gene Symbol
Cyp24a1
ORF Size (aa)
1545
ORF Size (bp)
1545 bp
RefSeq ID
NM_201635
RefSeq Synonyms
NM_201635, BC100059,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.