rat FCGR2B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Fcgr2b.
shADV-293258
Ad-r-FCGR2B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Fcgr2b (Fc fragment of IgG, low affinity IIb, receptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD32; FcgammaRIIB2; Fcgr2; FCRII
Description (Vector)
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Gene ID
289211
Gene Name (Vector)
Fc fragment of IgG, low affinity IIb, receptor
Gene Symbol
Fcgr2b
ORF Size (aa)
858
RefSeq ID
NM_175756
RefSeq Synonyms
NM_175756, BC091113,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.