rat NR1H3 shRNA silencing Adenovirus

Name
Ad-r-NR1H3-shRNA

Cat No
shADV-293107

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Nr1h3.

shADV-293107

Ad-r-NR1H3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Nr1h3 (nuclear receptor subfamily 1, group H, member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

LXRalpha

Description (Vector)

Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8 (By similarity).

Gene ID

58852

Gene Name (Vector)

nuclear receptor subfamily 1, group H, member 3

Gene Symbol

Nr1h3

ORF Size (aa)

1338

ORF Size (bp)

1338 bp

RefSeq ID

NM_031627

RefSeq Synonyms

NM_031627, BC088750,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.