rat NEUROD1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Neurod1.
shADV-293079
Ad-r-NEUROD1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Neurod1 (neuronal differentiation 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. Associates with the p300/CBP transcription coactivator complex to stimulates transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).
Gene ID
29458
Gene Name (Vector)
neuronal differentiation 1
Gene Symbol
Neurod1
ORF Size (aa)
1074
ORF Size (bp)
1074 bp
RefSeq ID
NM_019218
RefSeq Synonyms
NM_019218, BC094526, BC092367,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.