rat PASK shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Pask.
shADV-292445
Ad-r-PASK-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Pask (PAS domain containing serine/threonine kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells; however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate to respiratory regulation.
Gene ID
301617
Gene Name (Vector)
PAS domain containing serine/threonine kinase
Gene Symbol
Pask
ORF Size (aa)
4158
ORF Size (bp)
4158 bp
RefSeq ID
NM_001009362
RefSeq Synonyms
NM_001009362, BC087047,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.