rat SERPINA1 shRNA silencing Adenovirus

Name
Ad-r-SERPINA1-shRNA

Cat No
shADV-290832

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Serpina1.

shADV-290832

Ad-r-SERPINA1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Serpina1 (serpin family A member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AAT; Pi; Spi1

Description (Vector)

Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin|Function: Short peptide from AAT (SPAAT) is a reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).

Gene ID

24648

Gene Name (Vector)

serpin family A member 1

Gene Symbol

Serpina1

ORF Size (aa)

1236

ORF Size (bp)

1236 bp

RefSeq ID

NM_022519

RefSeq Synonyms

NM_022519, BC078824,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.