rat DBNL shRNA silencing Adenovirus

Name 
Ad-r-DBNL-shRNA
Cat No 
shADV-290672
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Dbnl.

shADV-290672
Ad-r-DBNL-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Dbnl (drebrin-like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
93
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
abp1; Sh3p7
Description (Vector)
Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.
Gene ID
83527
Gene Name (Vector)
drebrin-like
Gene Symbol
Dbnl
ORF Size (aa)
1311
ORF Size (bp)
1311 bp
RefSeq ID
NM_001277212
RefSeq Synonyms
NM_031352, NM_001277213, NM_001277212, NM_001277211, BC072483,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.