rat RRAGA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Rraga.
shADV-290469
Ad-r-RRAGA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Rraga (Ras-related GTP binding A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Raga
Description (Vector)
Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.
Gene ID
117044
Gene Name (Vector)
Ras-related GTP binding A
Gene Symbol
Rraga
ORF Size (aa)
942
ORF Size (bp)
942 bp
RefSeq ID
NM_053973
RefSeq Synonyms
NM_053973, BC061850,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.