human DOK5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DOK5.
shAAV-207249
AAV-h-DOK5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DOK5 (docking protein 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C20orf180; IRS-6; IRS6
Description (Vector)
DOK5 is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP.
Gene ID
55816
Gene Name (Vector)
docking protein 5
Gene Symbol
DOK5
HGNC ID
HGNC:16173
ORF Size (aa)
597
ORF Size (bp)
597 bp
RefSeq ID
NM_018431
RefSeq Synonyms
NM_177959, NM_018431, NM_001294161, BC008992,
Species
human
UniGene ID
Hs.656582
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.