mouse CDC42 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Cdc42.
shADV-280627
Ad-m-CDC42-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Cdc42 (cell division cycle 42). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI747189; AU018915
Description (Vector)
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration.
Gene ID
12540
Gene Name (Vector)
cell division cycle 42
Gene Symbol
Cdc42
ORF Size (aa)
576
RefSeq ID
NM_009861
RefSeq Synonyms
NM_009861, NM_001243769, BC064792,
Species
mouse
UniGene ID
Mm.475151
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.