human CDC42 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CDC42.
shADV-204757
Ad-h-CDC42-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CDC42 (cell division cycle 42). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDC42Hs; G25K; TKS
Description (Vector)
CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.
Gene ID
998
Gene Name (Vector)
cell division cycle 42
Gene Symbol
CDC42
HGNC ID
HGNC:1736
ORF Size (aa)
576
ORF Size (bp)
576 bp
RefSeq ID
NM_001791
RefSeq Synonyms
NM_044472, NM_001791, NM_001039802, BC018266, BC003682, BC002711,
Species
human
UniGene ID
Hs.690198
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.