human NSUN2 Over-expression AAV
This is an AAV expressing Human NSUN2.
AAV-217119
AAV-h-NSUN2
Ready-to-use AAV expressing Human NSUN2 (NOP2/Sun RNA methyltransferase family member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MISU; MRT5; SAKI; TRM4
Description (Vector)
NSUN2 encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Gene ID
54888
Gene Name (Vector)
NOP2/Sun RNA methyltransferase family member 2
Gene Symbol
NSUN2
HGNC ID
HGNC:25994
ORF Size (aa)
2304
ORF Size (bp)
2304 bp
RefSeq ID
NM_017755
RefSeq Synonyms
NM_017755, NM_001193455, BC137083, BC001041,
Species
human
UniGene ID
Hs.481526
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.