mouse NSUN2 shRNA silencing AAV

Cat. No: shAAV-266117

Availability: 4-5 weeks

Name: AAV-m-NSUN2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Nsun2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Nsun2
Gene Name: NOL1/NOP2/Sun domain family member 2
Gene ID: 28114
Gene Synonyms: D13Wsu123e; Misu
ORF Size: 1566 bp
RefSeq#: NM_145354
Gene Description: RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. Not able to modify tRNAs at positions 48 or 49. May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.
UniGene ID: Mm.260009