mouse NSUN2 shRNA silencing AAV

Name 
AAV-m-NSUN2-shRNA
Cat No 
shAAV-266117
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Nsun2.

shAAV-266117
AAV-m-NSUN2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Nsun2 (NOL1/NOP2/Sun domain family member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D13Wsu123e; Misu
Description (Vector)
RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. Not able to modify tRNAs at positions 48 or 49. May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.
Gene ID
28114
Gene Name (Vector)
NOL1/NOP2/Sun domain family member 2
Gene Symbol
Nsun2
ORF Size (aa)
1566
ORF Size (bp)
1566 bp
RefSeq ID
NM_145354
RefSeq Synonyms
NM_145354, BC013625,
Species
mouse
UniGene ID
Mm.260009

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.