mouse PAX6 shRNA silencing Adenovirus

Name
Ad-m-PAX6-shRNA

Cat No
shADV-277802

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Pax6.

shADV-277802

Ad-m-PAX6-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Pax6 (paired box 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

1500038E17Rik; AEY11; Dey; Gsfaey11; Pax-6; Sey

Description (Vector)

Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.

Gene ID

18508

Gene Name (Vector)

paired box 6

Gene Symbol

Pax6

ORF Size (aa)

1311

ORF Size (bp)

1311 bp

RefSeq ID

NM_013627

RefSeq Synonyms

NM_013627, NM_001310146, NM_001310145, NM_001310144, NM_001244202, NM_001244201, NM_001244200, NM_001244198, BC036957, BC011272,

Species

mouse

UniGene ID

Mm.3608

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.