mouse WT1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Wt1.
shADV-276348
Ad-m-WT1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Wt1 (Wilms tumor 1 homolog). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D630046I19Rik; Wt-1
Description (Vector)
Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
Gene ID
22431
Gene Name (Vector)
Wilms tumor 1 homolog
Gene Symbol
Wt1
ORF Size (aa)
1347
ORF Size (bp)
1347 bp
RefSeq ID
NM_144783
RefSeq Synonyms
NM_144783, BC148376,
Species
mouse
UniGene ID
Mm.389339
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.