mouse TUSC4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Nprl2.
shADV-275359
Ad-m-TUSC4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nprl2 (nitrogen permease regulator-like 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2810446G01Rik; G21; NPR2L; Tusc4
Description (Vector)
Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.
Gene ID
56032
Gene Name (Vector)
nitrogen permease regulator-like 2
Gene Symbol
Nprl2
ORF Size (aa)
1143
RefSeq ID
NM_018879
RefSeq Synonyms
NM_018879, BC026548,
Species
mouse
UniGene ID
Mm.11337
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.