human NLRP7 Over-expression AAV

Name 
AAV-h-NLRP7
Cat No 
AAV-216806
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NLRP7.

AAV-216806
AAV-h-NLRP7

Ready-to-use AAV expressing Human NLRP7 (NLR family pyrin domain containing 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CLR19.4; HYDM; NALP7; NOD12; PAN7; PYPAF3
Description (Vector)
NLRP7 encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. NLRP7 may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
199713
Gene Name (Vector)
NLR family pyrin domain containing 7
Gene Symbol
NLRP7
HGNC ID
HGNC:22947
ORF Size (aa)
2892
ORF Size (bp)
2892 bp
RefSeq ID
NM_139176
RefSeq Synonyms
NM_206828, NM_139176, NM_001127255, BC109125, BC109124,
Species
human
UniGene ID
Hs.351118

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.