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mouse TM7SF4 shRNA silencing Adenovirus

Name 
Ad-m-TM7SF4-shRNA
Cat No 
shADV-274306
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Dcstamp.

shADV-274306
Ad-m-TM7SF4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Dcstamp (dendrocyte expressed seven transmembrane protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
4833414I07Rik; DC-STAMP; FIND; mDC-STAMP; Tm7sf4
Description (Vector)
Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.
Gene ID
75766
Gene Name (Vector)
dendrocyte expressed seven transmembrane protein
Gene Symbol
Dcstamp
ORF Size (aa)
1413
ORF Size (bp)
1413 bp
RefSeq ID
NM_001289506
RefSeq Synonyms
NM_029422, NM_001289513, NM_001289512, NM_001289508, NM_001289506, BC145558, BC139146,
Species
mouse
UniGene ID
Mm.159563

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.