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mouse TLR8 shRNA silencing Adenovirus

Name 
Ad-m-TLR8-shRNA
Cat No 
shADV-274287
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Tlr8.

shADV-274287
Ad-m-TLR8-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Tlr8 (toll-like receptor 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Gene ID
170744
Gene Name (Vector)
toll-like receptor 8
Gene Symbol
Tlr8
ORF Size (aa)
3099
ORF Size (bp)
3099 bp
RefSeq ID
NM_133212
RefSeq Synonyms
NM_133212, NM_001313761, NM_001313760, BC132054,
Species
mouse
UniGene ID
Mm.196676

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.