mouse TGM3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Tgm3.
shADV-274119
Ad-m-TGM3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Tgm3 (transglutaminase 3, E polypeptide). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI893889; TG E; TG(E); TGase E; TGase-3; TGE; we
Description (Vector)
Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.
Gene ID
21818
Gene Name (Vector)
transglutaminase 3, E polypeptide
Gene Symbol
Tgm3
ORF Size (aa)
2082
ORF Size (bp)
2082 bp
RefSeq ID
NM_009374
RefSeq Synonyms
NM_009374, BC129891, BC129890,
Species
mouse
UniGene ID
Mm.2961
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.