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mouse SUPV3L1 shRNA silencing Adenovirus

Name 
Ad-m-SUPV3L1-shRNA
Cat No 
shADV-273475
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Supv3l1.

shADV-273475
Ad-m-SUPV3L1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Supv3l1 (suppressor of var1, 3-like 1 (S. cerevisiae)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
6330443E10Rik
Description (Vector)
Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
Gene ID
338359
Gene Name (Vector)
suppressor of var1, 3-like 1 (S. cerevisiae)
Gene Symbol
Supv3l1
ORF Size (aa)
2340
ORF Size (bp)
2340 bp
RefSeq ID
NM_181423
RefSeq Synonyms
NM_181423, BC049796,
Species
mouse
UniGene ID
Mm.235898

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.