rat SUPV3L1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Supv3l1.
shAAV-292846
AAV-r-SUPV3L1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Supv3l1 (Suv3 like RNA helicase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
Gene ID
294385
Gene Name (Vector)
Suv3 like RNA helicase
Gene Symbol
Supv3l1
ORF Size (aa)
2331
ORF Size (bp)
2331 bp
RefSeq ID
NM_001012462
RefSeq Synonyms
NM_001012462, BC089883,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.