mouse SLC27A1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Slc27a1.
shADV-272263
Ad-m-SLC27A1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Slc27a1 (solute carrier family 27 (fatty acid transporter), member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Fatp; FATP1
Description (Vector)
Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (By similarity).
Gene ID
26457
Gene Name (Vector)
solute carrier family 27 (fatty acid transporter), member 1
Gene Symbol
Slc27a1
ORF Size (aa)
1941
ORF Size (bp)
1941 bp
RefSeq ID
NM_011977
RefSeq Synonyms
NM_011977, BC028937,
Species
mouse
UniGene ID
Mm.38165
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.