mouse SIGMAR1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Sigmar1.
shADV-271989
Ad-m-SIGMAR1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Sigmar1 (sigma non-opioid intracellular receptor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Oprs1; Sig1R; sigma1R
Description (Vector)
Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration.
Gene ID
18391
Gene Name (Vector)
sigma non-opioid intracellular receptor 1
Gene Symbol
Sigmar1
ORF Size (aa)
672
ORF Size (bp)
672 bp
RefSeq ID
NM_011014
RefSeq Synonyms
NM_011014, NM_001286605, NM_001286551, NM_001286542, NM_001286541, NM_001286540, NM_001286539, NM_001286538, BC019930, BC002000,
Species
mouse
UniGene ID
Mm.425181
Recently Viewed Products
AAV-mIP2-DIO-TdTomato-WPRE
Cat No: VB5309
Ad-r-PITX1-shRNA
Cat No: shADV-290540
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.