mouse SCG5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Scg5.
shADV-271427
Ad-m-SCG5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Scg5 (secretogranin V). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
7B2; AI325031; Sgne-1; Sgne1
Description (Vector)
Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
Gene ID
20394
Gene Name (Vector)
secretogranin V
Gene Symbol
Scg5
ORF Size (aa)
639
ORF Size (bp)
639 bp
RefSeq ID
NM_009162
RefSeq Synonyms
NM_009162, BC029021,
Species
mouse
UniGene ID
Mm.4836
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.