mouse PPP2R2D shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ppp2r2d.
shADV-269233
Ad-m-PPP2R2D-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ppp2r2d (protein phosphatase 2, regulatory subunit B, delta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1300017E19Rik; D7Ertd753e; MDS026
Description (Vector)
B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity).
Gene ID
52432
Gene Name (Vector)
protein phosphatase 2, regulatory subunit B, delta
Gene Symbol
Ppp2r2d
ORF Size (aa)
1362
ORF Size (bp)
1362 bp
RefSeq ID
NM_026391
RefSeq Synonyms
NM_026391, NM_001347618, BC066022,
Species
mouse
UniGene ID
Mm.258739
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.