human NAGK Over-expression AAV

Name 
AAV-h-NAGK
Cat No 
AAV-216289
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human NAGK.

AAV-216289
AAV-h-NAGK

Ready-to-use AAV expressing Human NAGK (N-acetylglucosamine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
epididymis secretory sperm binding protein; glcNAc kinase; GNK; HSA242910; N-acetyl-D-glucosamine kinase; N-acetylglucosamine kinase
Description (eCommerce)
N-acetylglucosamine kinase (NAGK) converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. NAGK belongs to the group of N-acetylhexosamine kinases and is a prominent salvage enzyme of amino sugar metabolism in mammals [taken from NCBI Entrez Gene (GeneID: 55577)].
Description (Vector)
NAGK encodes a member of the N-acetylhexosamine kinase family. The encoded protein catalyzes the conversion of N-acetyl-D-glucosamine to N-acetyl-D-glucosamine 6-phosphate, and is the major mammalian enzyme which recovers amino sugars.
Gene ID
55577
Gene Name (eCommerce)
N-acetylglucosamine kinase
Gene Name (Vector)
N-acetylglucosamine kinase
Gene Symbol
NAGK
HGNC ID
HGNC:17174
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1035
ORF Size (bp)
1035 bp
Protein Name (eCommerce)
N-acetyl-D-glucosamine kinase
RefSeq ID
NM_017567
RefSeq Synonyms
NM_017567, NM_001330426, NM_001330425, BC005371, BC001029,
Research Areas
Kinase/Phosphatase,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism,signal_transduction
Species
human
Target Sentence
N-acetylglucosamine kinase (NAGK) converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. NAGK belongs to the group of N-acetylhexosamine kinases and is a prominent salvage enzyme of amino sugar metabolism in mammals [taken from NCBI Entrez Gene (GeneID: 55577)].
UniGene ID
Hs.7036
UniProt ID (eCommerce)
Q9UJ70

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.