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mouse PLXNA1 shRNA silencing Adenovirus

Name 
Ad-m-PLXNA1-shRNA
Cat No 
shADV-268913
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Plxna1.

shADV-268913
Ad-m-PLXNA1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Plxna1 (plexin A1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2600013D04Rik; mKIAA4053; NOV; PlexA1; Plxn1
Description (Vector)
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).
Gene ID
18844
Gene Name (Vector)
plexin A1
Gene Symbol
Plxna1
ORF Size (aa)
5685
ORF Size (bp)
5685 bp
RefSeq ID
NM_008881
RefSeq Synonyms
NM_008881, BC138023,
Species
mouse
UniGene ID
Mm.3789

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.