human MTMR6 Over-expression AAV

Name 
AAV-h-MTMR6
Cat No 
AAV-216024
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MTMR6.

AAV-216024
AAV-h-MTMR6

Ready-to-use AAV expressing Human MTMR6 (myotubularin related protein 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
myotubularin-related protein 6
Description (eCommerce)
Myotubularin-related protein 6 (MTMR6) is a phosphatase that acts on lipids with a phosphoinositol headgroup. MTMR6 acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y217].
Gene ID
9107
Gene Name (eCommerce)
myotubularin related protein 6
Gene Name (Vector)
myotubularin related protein 6
Gene Symbol
MTMR6
HGNC ID
HGNC:7453
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1866
ORF Size (bp)
1866 bp
Protein Name (eCommerce)
Myotubularin-related protein 6
RefSeq ID
NM_004685
RefSeq Synonyms
NM_004685, BC040012,
Research Areas
Kinase/Phosphatase,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism,signal_transduction
Species
human
Target Sentence
Myotubularin-related protein 6 (MTMR6) is a phosphatase that acts on lipids with a phosphoinositol headgroup. MTMR6 acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y217].
UniGene ID
Hs.643702
UniProt ID (eCommerce)
Q9Y217

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.