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mouse NUDT3 shRNA silencing Adenovirus

Name 
Ad-m-NUDT3-shRNA
Cat No 
shADV-266193
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Nudt3.

shADV-266193
Ad-m-NUDT3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nudt3 (nudix (nucleotide diphosphate linked moiety X)-type motif 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1110011B09Rik; AA960325; Dipp; Dipp1
Description (Vector)
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6 (inositol hexakisphophate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
Gene ID
56409
Gene Name (Vector)
nudix (nucleotide diphosphate linked moiety X)-type motif 3
Gene Symbol
Nudt3
ORF Size (aa)
507
ORF Size (bp)
507 bp
RefSeq ID
NM_019837
RefSeq Synonyms
NM_019837, NM_001291046, BC046805, BC016534,
Species
mouse
UniGene ID
Mm.473041

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.