mouse NMNAT2 shRNA silencing Adenovirus

Name 
Ad-m-NMNAT2-shRNA
Cat No 
shADV-265882
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Nmnat2.

shADV-265882
Ad-m-NMNAT2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nmnat2 (nicotinamide nucleotide adenylyltransferase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AI843915; D030041I09Rik; PNAT1; PNAT2
Description (Vector)
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Cannnot use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NAAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+).
Gene ID
226518
Gene Name (Vector)
nicotinamide nucleotide adenylyltransferase 2
Gene Symbol
Nmnat2
ORF Size (aa)
924
ORF Size (bp)
924 bp
RefSeq ID
NM_175460
RefSeq Synonyms
NM_175460, BC089007,
Species
mouse
UniGene ID
Mm.40548

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.