mouse MEF2C shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Mef2c.
shADV-264473
Ad-m-MEF2C-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mef2c (myocyte enhancer factor 2C). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5430401D19Rik; 9930028G15Rik; AV011172; Mef2
Description (Vector)
Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Gene ID
17260
Gene Name (Vector)
myocyte enhancer factor 2C
Gene Symbol
Mef2c
ORF Size (aa)
1329
ORF Size (bp)
1329 bp
RefSeq ID
NM_025282
RefSeq Synonyms
NM_025282, NM_001347581, NM_001347580, NM_001347579, NM_001347578, NM_001347577, NM_001347576, NM_001347575, NM_001347574, NM_001347573, NM_001347572, NM_001347571, NM_001347569, NM_001347568, NM_001347567, NM_001347566, NM_001347564, NM_001170537, BC057650, BC037731, BC026841,
Species
mouse
UniGene ID
Mm.451574
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.