mouse MARCH8 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse March8.
shADV-264263
Ad-m-MARCH8-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse March8 (membrane-associated ring finger (C3HC4) 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1300017E09Rik; MARCH-VIII; Mir
Description (Vector)
E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS.
Gene ID
71779
Gene Name (Vector)
membrane-associated ring finger (C3HC4) 8
Gene Symbol
8-Mar
ORF Size (aa)
861
ORF Size (bp)
861 bp
RefSeq ID
NM_027920
RefSeq Synonyms
NM_027920, NM_001302385, NM_001302384, NM_001302383, BC053090, BC050908,
Species
mouse
UniGene ID
Mm.27064
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.