mouse MAFB shRNA silencing Adenovirus

Name 
Ad-m-MAFB-shRNA
Cat No 
shADV-264083
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Mafb.

shADV-264083
Ad-m-MAFB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mafb (v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
kr; Kreisler; Krml; Krml1
Description (Vector)
Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Gene ID
16658
Gene Name (Vector)
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
Gene Symbol
Mafb
ORF Size (aa)
972
ORF Size (bp)
972 bp
RefSeq ID
NM_010658
RefSeq Synonyms
NM_010658, BC038256, BC016434,
Species
mouse
UniGene ID
Mm.330745

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.