human MRPL37 Over-expression AAV

Name
AAV-h-MRPL37

Cat No
AAV-215813

Availability
4-5 weeks

This is an AAV expressing Human MRPL37.

AAV-215813

AAV-h-MRPL37

Ready-to-use AAV expressing Human MRPL37 (mitochondrial ribosomal protein L37). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

L2mt; L37mt; MRP-L2; MRP-L37; MRPL2; RPML2

Description (Vector)

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.

Gene ID

51253

Gene Name (Vector)

mitochondrial ribosomal protein L37

Gene Symbol

MRPL37

HGNC ID

HGNC:14034

ORF Size (aa)

1272

ORF Size (bp)

1272 bp

RefSeq ID

NM_016491

RefSeq Synonyms

NM_016491, NM_001330602, BC000041,

Species

human

UniGene ID

Hs.584908

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.