human MPZL1 Over-expression AAV

Name 
AAV-h-MPZL1
Cat No 
AAV-215738
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MPZL1.

AAV-215738
AAV-h-MPZL1

Ready-to-use AAV expressing Human MPZL1 (myelin protein zero like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
immunoglobulin family transmembrane protein; MPZL1b; myelin protein zero-like protein 1; protein zero related; Protein zero-related; PZR; PZR1b; PZRa; PZRb
Description (eCommerce)
Protein zero-related (PZR) is a cell surface receptor involved in signal transduction processes. PZR recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. It is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95297].
Gene ID
9019
Gene Name (eCommerce)
myelin protein zero like 1
Gene Name (Vector)
myelin protein zero like 1
Gene Symbol
MPZL1
HGNC ID
HGNC:7226
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
810
ORF Size (bp)
810 bp
Protein Name (eCommerce)
Myelin protein zero-like protein 1
RefSeq ID
NM_024569
RefSeq Synonyms
NM_024569, NM_003953, NM_001146191, BC007881,
Research Areas
EGFR Signaling,Immunology,Signal Transduction,T-cell Receptor Signaling
Research Areas (Faceted)
signal_transduction,immunology
Species
human
Target Sentence
Protein zero-related (PZR) is a cell surface receptor involved in signal transduction processes. PZR recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. It is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95297].
UniGene ID
Hs.603116
UniProt ID (eCommerce)
O95297

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.