human MPZ Over-expression AAV

Name 
AAV-h-MPZ
Cat No 
AAV-215737
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MPZ.

AAV-215737
AAV-h-MPZ

Ready-to-use AAV expressing Human MPZ (myelin protein zero). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CHM; CMT1; CMT1B; CMT2I; CMT2J; CMT4E; CMTDI3; CMTDID; DSS; HMSNIB; MPP; P0
Description (Vector)
MPZ encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies.
Gene ID
4359
Gene Name (Vector)
myelin protein zero
Gene Symbol
MPZ
HGNC ID
HGNC:7225
ORF Size (aa)
777
RefSeq ID
NM_000530
RefSeq Synonyms
NM_001315491, NM_000530, BC006491,
Species
human
UniGene ID
Hs.591486

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.