mouse KCNJ12 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Kcnj12.
shADV-262653
Ad-m-KCNJ12-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Kcnj12 (potassium inwardly-rectifying channel, subfamily J, member 12). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IRK-2; IRK2; Kir2.2; MB-IRK2
Description (Vector)
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.
Gene ID
16515
Gene Name (Vector)
potassium inwardly-rectifying channel, subfamily J, member 12
Gene Symbol
Kcnj12
ORF Size (aa)
1284
ORF Size (bp)
1284 bp
RefSeq ID
NM_010603
RefSeq Synonyms
NM_010603, NM_001267593, BC116677, BC115970,
Species
mouse
UniGene ID
Mm.4970
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.